GAPDH抗體;GAPDH;Rabbit anti-GAPDH Polyclonal Antibody

Rabbit

GAPDH

Human, Mouse, Rat, Rabbit, Porcine, Sheep, Goose, Chicken, Bovine, Pig, Rattus norvegicu, Duck, Broiler Chick, Cat, Zebrafish

WB: 1:10000-200000, IHC-P: 1:100-500, IHC-F: 1:100-500, IF: 1:100-500

Predicted molecular weight: 37kDa

GAPDH protein of rabbit

Liquid

1mg/mL

affinity purified by Protein A

Polyclonal Antibody

IgG

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unlabeled

Unmodified

Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 38kDa subunits.

細胞骨架，細胞質，膜，細胞核

P04406