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簡要描述：西維來司鈉 150374-95-1A selective leukocyte elastase inhibitor
產品型號：abs42236361廠商性質：生產廠家更新時間：2025-11-20訪 問 量：1825產品分類
Product Category詳細介紹
| 品牌 | absin | 貨號 | abs42236361 |
|---|---|---|---|
| 規(guī)格 | 10mg;50mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | A selective leukocyte elastase inhibitor |
西維來司鈉 150374-95-1
| 產品描述 | |
| 描述 | Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM). Through in vitro observations, Sivelestat functions by blocking LTB4-induced neutrophil transmigration and NF-κB activation. |
| 應用 | A selective leukocyte elastase inhibitor |
| 純度 | ≥98% |
| 儲存/保存方法 | Desiccate at room temperature |
| 形態(tài) | Solid |
| 基本信息 | |
| 別名 | N-[2-[[[4-(2,2-二甲基-1-氧代丙氧基)苯基]磺酰]氨基]苯甲酰]-(S)-甘氨suan單鈉鹽;N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt |
| IC50 | Leukocyte elastase: IC50 = 44 nM; neutrophil elastase: IC50 = 44 nM (human); Leukocyte elastase: IC50 = 19-49 nM (rabbit, rat, hamster and mouse) |
| Ki 數(shù)據 | neutrophil elastase: Ki= 0.2 nM (human) |
| 可溶性/溶解性 | Soluble in DMSO (50 mM). |
| MDL | MFCD08461731 |
| PubChem CID | 23664980 |
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